The Painted House (Karlovo namesti No. 53) was built in the late 16th century by the Venice merchant Francesco Calligardi, who used it as a store to sell colonial goods. Francesco was soon to be called Frantisek and his imposing house started to be referred to as 'Frantisek's house'. Later owners of the house had its graffito facade decoration covered up with lime. It was not until 1903 when it was rediscovered by Josef Kozlansky, a teacher at the Trebic Grammar School. Below the ledge of the building there are several paintings of a hunter and a lion, the space between individual windows is covered with pictures of Biblical figures. The bay window is decorated with pictures of men in 16th-century folk costumes whereas the lateral facade facing Hasskova Street (Hasskova ulice) carries pictures of figures with hunting gear. All this is framed with varied ornamental decoration.

The sparkling black and white graffito decoration, which looked as if it was actually painted, had been pleasing the eyes of the inhabitants of Trebic until the house succumbed to the ravages of time. Its stone walls tilted forward into the street and the whole building turned out to be statically unstable. Therefore, in the 1980s it was decided to carry out a thorough restoration of the building. The restoration included its spectacular interior vaulting, the daring columns, the open-air terrace with arches, the atrium and several rooms.

Furthermore, the graffito decoration was cleaned. The newly adapted first floor provided a unique space for a showroom, the middle floor houses a ceremony hall, whereas the upper level of the building is occupied by a radio studio and the editorial office of Zpravodaj mesta Trebice ('The Trebic Times' - a local newspaper). After the painstaking restoration the Painted House became once again the cream of the city's historic monuments.